Hormone Storage Granules in the Beef Anterior Pituitary
نویسندگان
چکیده
A method is described for isolation of relatively large quantities of large and small hormone storage granules from the beef adenohypophysis. The hormone storage granules are highly purified, as indicated by ultrastructural and biochemical criteria. The average size of large granules is 400 mmicro and of small granules is 220 mmicro. The large granules contain growth hormone and prolactin; the small granules contain high concentrations of follicle-stimulating, luteinizing, and thyroid-stimulating hormones. An alkaline protease with a pH optimum of 8.3 is associated with the small granule fraction.
منابع مشابه
Synthesis and secretion of growth hormone in the rat anterior pituitary. II. Properties of the isolated growth hormone storage granules.
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عنوان ژورنال:
- The Journal of Cell Biology
دوره 40 شماره
صفحات -
تاریخ انتشار 1969